|AGRICULTURAL AND FORESTRY SCIENCES
|LEVEL OF STUDIES
|Chemistry of Natural Products and Applications
If the ECTS Credits are distributed in distinct parts of the course e.g. lectures, labs etc. If the ECTS Credits are awarded to the whole course, then please indicate the teaching hours per week and the corresponding ECTS Credits.
|TEACHING HOURS PER WEEK
|Lectures and laboratory course
|Please, add lines if necessary. Teaching methods and organization of the course are described in section 4.
Background, General Knowledge, Scientific Area, Skill Development
|TEACHING & EXAMINATION LANGUAGE:
|COURSE OFFERED TO ERASMUS STUDENTS:
- LEARNING OUTCOMES
|Please describe the learning outcomes of the course: Knowledge, skills and abilities acquired after the successful completion of the course.
|The secondary metabolic compounds of living organisms, which characterize the species that produces them, are referred to as natural products. The wide variety of structures created by nature and associated with the bioactivity of these products, attracted the interest of scientists from a very early age to study their chemistry and their applications. Today the knowledge in this field has spread enormously and contributes a lot to the improvement of human life. The aim of the course is to give basic knowledge concerning organic compounds that are characterized as products of both primary and secondary metabolism, to describe the methods for their isolation and characterization, to study their interaction with both the natural environment and with man and finally to investigate their possible utilization.
Upon successful completion of the course, postgraduate students will be able to:
• Describe and identify the structural characteristics of each category of compounds belonging to the broader category of natural products.
• Study and understand the stereochemistry of natural products that is directly related to their biological action, as well as to know selected methods of isolation and analysis.
• Recognize the importance of natural products in medicine, cosmetology, agriculture, daily life and therefore the need for their production on a large scale which makes it necessary to have a good knowledge of their chemistry and application.
• Gaining knowledge about how and why plants produce such a wide range of metabolites gives us new ideas on how plants use these compounds to prevent predators and pathogens, attract and prevent pollinators, inhibit other plants by competing with themselves for own resources, and defending themselves from environmental stress.
|Name the desirable general skills upon successful completion of the module
|Search, analysis and synthesis of data and information,
Adaptation to new situations
Working in an international environment
Working in an interdisciplinary environment
Production of new research ideas
|Project design and management
Equity and Inclusion
Respect for the natural environment
Demonstration of social, professional and moral responsibility and sensitivity to gender issues
Promoting free, creative and inductive reasoning
§ Independent work
§ Development of inductive reasoning
- COURSE CONTENT
|Lecture program of the course ‘Natural Product Chemistry and Applications’
1st Week, Phytochemicals: The chemical composition of plants.
2nd Week, Phenolic compounds – Investigation of antioxidant activity.
3rd Week, Alkaloids.
4th Week, Organic acids.
5th Week, Cellulose-hemicellulose, Pectins-Lignins.
6th Week, Aromatic and medicinal plants – Essential oils.
7th Week, Aromatic and medicinal plants – Terpenes.
8th Week, Vitamins.
9th Week, Organosulfur compounds: Part of I.
10th Week, Organosulfur compounds: Part II.
11th Week, Mode of action of natural products.
12th Week, Beneficial action of natural products.
13th Week, Allelopathy.
14th Week, Submission and presentation of bibliographic review work
15th Week, Final semester examinations
- LEARNING & TEACHING METHODS – EVALUATION
Face to face, Distance learning, etc.
|USE OF INFORMATION & COMMUNICATIONS TECHNOLOGY (ICT)
Use of ICT in Teaching, in Laboratory Education, in Communication with students
|§ Power point, videos
§ Lab techniques presentation
The ways and methods of teaching are described in detail.
Lectures, Seminars, Laboratory Exercise, Field Exercise, Bibliographic research & analysis, Tutoring, Internship (Placement), Clinical Exercise, Art Workshop, Interactive learning, Study visits, Study / creation, project, creation, project. Etc.
The supervised and unsupervised workload per activity is indicated here, so that total workload per semester complies to ECTS standards.
Description of the evaluation process
Assessment Language, Assessment Methods, Formative or Concluding, Multiple Choice Test, Short Answer Questions, Essay Development Questions, Problem Solving, Written Assignment, Essay / Report, Oral Exam, Presentation in audience, Laboratory Report, Clinical examination of a patient, Artistic interpretation, Other/Others
Please indicate all relevant information about the course assessment and how students are informed
In order to pass this course, each student must complete all of the following compulsory:
I. Written final exam (60%) which includes:
– Multiple choice questions
– Comparative evaluation of theory elements
II. Submission and presentation of review research (40%)
- SUGGESTED BIBLIOGRAPHY
· Leland J. Cseke, Ara Kirakosyan, Peter B. Kaufman, Sara L. Warber, James A. Duke and Harry L. Brielmann. Natural Products from Plants. Second Edition. 2006.
· Steven M. Colegate and Russell J. Molyneux. Bioactive Natural Products: Detection, Isolation, and Structural Determination. Second Edition. 2008.
· Raphael Ikan. Selected Topics in the Chemistry of Natural Products. 2008.
· K. Hόsnό Can BasΈer and Gerhard Buchbauer. Handbook of Essential Oils: Science, Technology and Applications. 2010.
· Pengelly Adrew. The Constituents of Medicinal Plants: An Introduction to the Chemistry of Therapeutics of Herbal Medicine. Second Edition. 2004.
· Sukhdev Swami Handa, Suman Preet Singh Khanuja, Gennaro Longo and Dev Dutt Rakesh. Extraction Technologies for Medicinal and Aromatic Plants. 2008.